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A single dose of intramuscular (IM) or intravenous (IV) methylprednisolone doesn't improve long-term pain scores in patients with low back pain and sciatica and produces conflicting effects on function. Oral prednisone (9-day taper) doesn't improve pain or function in patients with back pain and sciatica. A single IM dose of methylprednisolone doesn't improve pain scores or function in patients with back pain without sciatica (strength of recommendation: B , randomized controlled trials [RCTs]). No trials of corticosteroids for back pain reported an increase in adverse outcomes, but studies were small, and only short-term (1 month) follow-up data are available. A double-blind RCT of 82 patients who reported to an emergency department with acute low back pain and sciatica compared the efficacy of a single IM dose of 160 mg methylprednisolone with placebo, get a prescription for steroids online. COVID-19 is present and everything has changed, get a prescription for steroids online.
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